教学方向:
承担本科生及硕士研究生动物生物化学和免疫学等课程。
研究方向:
哺乳动物早期胚胎发育过程中,母源效应因子的作用机制研究。
1、2016-2018年主持北京市自然基金面上项目:BCAS2在精子发生中的调控作用
2、2017-2018年主持北京市教委科研计划项目:母源因子ZEBD3在早期胚胎发育中的机制研究
1、Liu W Wang F, Xu Q, Shi J, Zhang X, Lu X, Gao Z, Ma H, Zhao Z, Duan E, Gao F, Gao S*,Yi Z*, Li L*. BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.Nature Communications. 2017 Jan 27; 8:14182. (IF, 12.1).
2、Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, Xiang Y, Liu W, Chen J*,Yi Z*, and Li L*. Trp-Asp (WD) repeat domain 1 is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation.Journal of Biological Chemistry. 2017 Jan 27; 292(4):1438-1448. (IF, 4.2)
3、Liu Y, Lu X, Shi J, Yu X, Zhang X, Zhu K,Yi Z, Duan E, Li L. BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis. .Journal of Molecular Cell Biology.2016 Aug; 8(4):366-8. (IF, 6.0).
4、Xu Q, Wang F, Xiang Y, Zhang X, Zhao Z, Gao Z, Liu W, Lu X, Liu Y, Yu X, Wang H, Huang J,Yi Z, Gao S, Li L. Maternal BCAS2 protects genomic integrity in mouse early embryonic development.Development. 2015 Nov 15; 142(22):3943-53. (IF, 5.8).
5、Yu X.,Yi Z., Gao Z, ChenX., Wang Z., ZhengP., ZhuM., SunQ., Dean J., Li L. The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics.Nat. Commun.2014 Sep 11; 5:4887. (IF, 11.5).